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IGF-1R inhibitor-5 (compound 19) is a potent inhibitor of IGF-1R, with the IC50 of 6 μM. IGF-1R inhibitor-5 has the potential for the research of cancer[1].

[1] East China University of Science and Technology, et al. Use of 5-substituted-2, 4-thiazolidinediones in preparation of medicaments for modulating insulin-like growth factor 1 receptor. World Intellectual Property Organization, WO2011063602 A1 2011-06-03