MT477 (33, 100, 1000 μg/kg; i.p.; once a day on days 1, 4, 8, 16, 18, 20) shows antitumor activity[1].
| Animal Model: | 6-week-old male nude mice (A431 cells) [1] |
| Dosage: | 33, 100, 1000 μg/kg |
| Administration: | I.p.; once a day on days 1, 4, 8, 16, 18, 20 |
| Result: | Significant decreased in tumor volume of 24.5% by the third week at 1 mg/kg. |
| Animal Model: | 6-week-old male nude mice (H226 cells) [1] |
| Dosage: | 1 mg/kg |
| Administration: | I.p.; once a day on days 1, 4, 8, 20, 24, 28 |
| Result: | Inhibited tumor growth by 43.6% and observed no weight loss. |
