312722-60-4

Name	NVP-SAA 164
CAS	312722-60-4
Molecular Formula	C36H45N5O5S
MDL Number	MFCD19443778
Molecular Weight	659.84
MOL File	312722-60-4.mol

Synonyms

SAA164 SAA-164 SAA 164 NVP-SAA 164 [1-[4-[2,2-DI(PHENYL)ETHYLAMINO]-3-(MORPHOLINE-4-CARBONYL)PHENYL]SULFONYLPIPERIDIN-4-YL]-(4-METHYLPIPERAZIN-1-YL)METHANONE

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Chemical Properties

Boiling point	871.0±75.0 °C(Predicted)
density	1.275±0.06 g/cm3(Predicted)
pka	6.80±0.10(Predicted)

Hazard Information

Description

NVP-SAA164 is a nonpeptide bradykinin B1 receptor antagonist.

Uses

NVP-SAA164 is an orally active nonpeptide kinin B1 receptor antagonist. NVP-SAA164 reverses CFA (Complete Freund's adjuvant) (HY-153808)-induced mechanical hyperalgesia and desArg10KD-induced hyperalgesia in hB1-KI mice, and is inactive in a model of inflammatory pain in wild-type mice[1].

References

[1] Fox A, et al. Antihyperalgesic activity of a novel nonpeptide bradykinin B1 receptor antagonist in transgenic mice expressing the human B1 receptor. Br J Pharmacol. 2005 Apr;144(7):889-99. DOI:10.1038/sj.bjp.0706139

Supplier

Jinan Yaoyan Pharmaceutical Co., Ltd.

Telephone

Websitehttps://www.chemicalbook.com/ShowSupplierProductsList30574/0_EN.htm

Nanjing Meihao Pharmaceutical Technology Co., Ltd.

Telephonemeitaochem@126.com

Websitehttps://www.chemicalbook.com/ShowSupplierProductsList31244/0_EN.htm

JinOu Biomedical (Nanjing) Co., Ltd.

Telephone 13000000000

Websitehttps://www.chemicalbook.com/ShowSupplierProductsList1596079/0_EN.htm

TargetMol Chemicals Inc.

Telephone 15002134094

Websitehttps://www.targetmol.cn/

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