ChemicalBook CAS DataBase List 3036109-10-8

3036109-10-8

Name	Benzo[h]quinoline-2-methanamine, N-(4-methoxyphenyl)-4-[(4-methoxyphenyl)amino]-
CAS	3036109-10-8
Molecular Formula	C28H25N3O2
Molecular Weight	435.52
MOL File	3036109-10-8.mol

Chemical Properties

Boiling point	633.0±55.0 °C(predicted)
density	1.262±0.06 g/cm3(Temp: 20 °C; Press: 760 Torr)(predicted)
form	Solid
pka	7.31±0.40(predicted)
color	Light yellow to yellow

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Animal Model:	DA-MB-231 Orthotopic Mouse Xenograft Mammary Tumor Model^[1]
Dosage:	50 and 250 mg/kg; Once daily for 21 days
Administration:	Gavage administration (i.g.)
Result:	Significantly inhibited tumor growth with 49.1% inhibition. Reduced the Protein levels for BRD4, Mucin5AC, c-Myc, CDK4, and CDK6, upregulated the p21 protein.