30339-32-3

This product is white needle-shaped crystals, mp 169.5～170℃, [α]²¹_D＝69～69.4°(95% ethanol, C≈0.5), insoluble in water, soluble in organic solvents such as benzene, toluene, ethanol, etc.

(R)-1-Phenyl-2-(p-tolyl)ethylamine is a new resolving base for Ibuprofen (I140000); a selective cyclooxygenase inhibitor (IC50=14.9uM). Ibuprofen inhibits PGH synthase-1 and PGH synthase-2 with comparable potency.