HDAC6-IN-38 (Compound Z-7) is an inhibitor for histone deacetylase 6 (HDAC6), with an IC50 of 3.25 nM. HDAC6-IN-38 inhibits proliferation of cells MGC 803[1].
IC 50
HDAC6: 3.11 nM (IC50); HDAC1: 20.5 nM (IC50)
References
[1] Ma L, et al., Novel indole HDAC6 small molecule inhibitor, preparation method and application. CN117603123A.