(+)-Sotalol (8 mg/kg, i.v.) suppresses the induction of ventricular tachyarrhythmias by programmed stimulation in dogs[3].
Animal Model:
Programmed stimulated Dogs[3]
Dosage:
8 mg/kg
Administration:
Intravenous injection (i.v.)
Result:
Increased normal zone ventricular refractoriness, and prevented propagation of programmed ventricular extra-stimuli of sufficient prematurity to elicit tachyarrhythmias.
