3022-11-5

D-Luciferin 6'-methyl ether sodium salt is an inhibitor of firefly luciferase light producing system. It is useful in chemiluminescent dual assay systems with both luciferase and cytochrome P450 enzymes
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D-Luciferin 6'-methyl ether sodium salt is a firefly luciferase inhibitor. D-Luciferin 6'-methyl ether sodium salt is a cofactor in Luc-catalyzed synthesis of dinucleoside polyphosphates[1][2].

[1] Khnouf R, et al. Cell-free expression of soluble and membrane proteins in an array device for drug screening. Anal Chem. 2010 Aug 15;82(16):7021-6. DOI:10.1021/ac1015479
[2] Fraga H, et al. Firefly luciferase produces hydrogen peroxide as a coproduct in dehydroluciferyl adenylate formation. Chembiochem. 2006 Jun;7(6):929-35. DOI:10.1002/cbic.200500443