Uses
JWZ-7-7-Neg1 is a transcriptional chemical inducers of proximity (TCIP) with negative chemical control. JWZ-7-7-Neg1 reduces the ability to bind to BRD4 or BCL6, so it has less cytotoxicity to DLBCL cells, in compared with JWZ-7-7[1].
References
[1] Crabtree GR, et al., Compositions, systems, and methods for modulating a target gene. WO2023215311.
