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1-Palmitoyl-2-oleoyl-rac-glycerol is a monounsaturated diacylglycerol used to increase the activity of the ARF1 GTPase-activating protein on membrane-bound ARF1GTP.

1-Palmitoyl-2-oleoyl-sn-glycerol can be used in methods to enhance radiotherapy using ferroptosis inducers as radiosensitizers for identifying and treating a subject with a cancer that is resistant to radiotherapy.

ChEBI: 1-palmitoyl-2-oleoyl-sn-glycerol is a 1,2-diacyl-sn-glycerol with palmitoyl as the 1-acyl group and oleoyl as the 2-acyl group. It has a role as a mouse metabolite. It is a 1,2-diacyl-sn-glycerol and a 1-palmitoyl-2-oleoylglycerol. It is an enantiomer of a 2-oleoyl-3-palmitoyl-sn-glycerol.