STING agonist-30 is a potent STING agonist. STING agonist-30 exhibits STING-dependent immune activation. STING agonist-30 has extensive inhibitory effects on various viruses, including the herpes simplex virus (HSV), rotavirus, and severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)[1].
References
[1] Zang R, et, al. Design and syntheses of a bimolecular STING agonist based on the covalent STING antagonist. Eur J Med Chem. 2023 Mar 15;250:115184. DOI:10.1016/j.ejmech.2023.115184
