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4H,5H-pyrazolo pyrazoloapyrimidinone Larotrectinib PPO Impurity Pyrazolo[1,5-a]pyrimidin-5-ol 1H-pyrazolo[1,5-a]pyrimidin-5-one 5-Hydroxypyrazolo[1,5-a]pyrimidine 4H,5H-pyrazolo[1,5-a]pyriMidin-5-one Pyrazoland [1,5-a] pyrimidine-5 (4H) -ONE pyrazolo[1,5-a]pyrimidin-5(4H)-one(WXC06578) Larotrectinib Impurity 6（Larotrectinib PPO Impurity） 5-Hydroxypyrazolo[1,5-a]pyrimidine ISO 9001：2015 REACH