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CAS DataBase List
2898381-63-8
2898381-63-8
Name
HDAC/NAMPT-IN-1
CAS
2898381-63-8
Molecular Formula
C19H21N5O2
Molecular Weight
351.4
MOL File
2898381-63-8.mol
Synonyms
HDAC/NAMPT-IN-1
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Chemical Properties
Boiling point
653.2±55.0 °C(predicted)
density
1.262±0.06 g/cm3(Temp: 20 °C; Press: 760 Torr)(predicted)
pka
12.55±0.23(predicted)
Hazard Information
Uses
HDAC/NAMPT-IN-1 (compound 39h) is a dual inhibitor of HDAC and NAMPT with IC50 values of 0.72-37081 nM and 1618 nM[1].
References
[1] Kairui Yue, et al. HDAC/NAMPT dual inhibitors overcome initial drug-resistance in p53-null leukemia cells. Eur J Med Chem. 2024. DOI:
10.1016/j.ejmech.2024.116127
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Shanghai Beckham Medical Technology Co., Ltd
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https://www.chemicalbook.com/ShowSupplierProductsList16976/0_EN.htm
TargetMol Chemicals Inc.
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15002134094
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https://www.targetmol.cn/
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