277333-45-6

JA2 is an inhibitor of metalloendopeptidase 24.15 that can potentiate the hypotensive response to bradykinin in rat[1].

[1] Alessandra Linardi, et al. Peptidase activities in rats treated chronically with N(omega)-nitro-L-arginine methyl ester (L-NAME). Biochem Pharmacol. 2004 Jul 15;68(2):205-14. DOI:10.1016/j.bcp.2004.03.016