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Diisooctylphosphinic acid (DiOPA) may be used in the following studies:

• As the surface passivating ligand in the synthesis of magic-sized CdSe and CdTe nanocrystals.
• As extractant in the extraction of Indium(III) from sulfate solutions.
• As ligand to investigate the solubility of four copper ligand systems in supercritical CO₂.
• As acid ligand for the Supercritical fluid extraction (SFE) of divalent metals (Zn²⁺, Cu²⁺, Pb²⁺, Cd²⁺ and Cr³⁺) from sand and fly ash using CO₂.

Diisooctylphosphinic Acid functions as a surface passivating ligand in the synthesis of magic-sized cadmium selenide and cadmium telluride nanocrystals.

Diisooctylphosphinic acid is an organophosphorous acid.