ChemicalBook CAS DataBase List 2755454-90-9

2755454-90-9

Name	1H-Imidazole-5-carboxamide, 4-(1H-benzimidazol-2-yl)-N-cyclohexyl-
CAS	2755454-90-9
Molecular Formula	C17H19N5O
Molecular Weight	309.37
MOL File	2755454-90-9.mol

Chemical Properties

density	1.34±0.1 g/cm3(Predicted)
pka	9.89±0.10(Predicted)

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Animal Model:	Six-week-old female NOD/SCID mice, MDA-MB-231 xenograft^[1]
Dosage:	5 mg/kg, 15 mg/kg
Administration:	Intraperitoneal injection, every 3 days for 3 weeks
Result:	Suppressed human TNBC tumor growth in a dose-dependent manner and resulted in a concentration-dependent upregulation of LC3B-II, p62, γH2AX and PARP.