SUCNR1-IN-1 (Compound 20) is a SUCNR1 inhibitor (IC50: 88 nM for hSUCNR1). SUCNR1-IN-1 can be used for research of rheumatoid arthritis, liver fibrosis, or obesity[1].
References
[1] Velcicky J, et al. Discovery and Optimization of Novel SUCNR1 Inhibitors: Design of Zwitterionic Derivatives with a Salt Bridge for the Improvement of Oral Exposure. J Med Chem. 2020 Sep 10;63(17):9856-9875. DOI:10.1021/acs.jmedchem.0c01020
