27098-03-9

Botryodiplodin is a mycotoxin isolated from Penicillium roqueforti. Botryodiplodin inhibits the growth of some Gram-positive and Gram-negative bacteria and can also induce DNA-protein cross-links in mammalian cells, inhibiting the synthesis of DNA, RNA, and protein[1][2].

ChEBI: Botryodiplodin is a member of oxolanes.

[1] Moulé Y, et al. DNA-protein cross-linking by the mycotoxin, botryodiplodin, in mammalian cells[J]. Carcinogenesis, 1982, 3(2): 211-214. DOI:10.1093/carcin/3.2.211
[2] Moulé Y, et al. Mutagenicity of the mycotoxin botryodiplodin in the Salmonella typhimurium/microsomal activation test[J]. Environmental Mutagenesis, 1981, 3(3): 287-291. DOI:10.1002/em.2860030311