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LY 43578 is an aromatase inhibitor.

LY43578 is an orally active aromatase inhibitor. LY43578 inhibits P-450-dependent p-nitroanisole O-demethylation and ethylmorphine N-demethylation in hepatic microsomes isolated from rat, with the IC50 of 0.3 and 5 μΜ, respectively. LY43578 can be used for neurological disorder study[1][2].

[1] Lindstrom TD, et al. Disposition of the aromatase inhibitor LY56110 and associated induction and inhibition studies in rats, dogs, and monkeys. Fundam Appl Toxicol. 1987;8(4):595-604. DOI:10.1016/0272-0590(87)90144-8
[2] Gonzalez MI, et al. Injection of an aromatase inhibitor after the critical period of sexual differentiation. Pharmacol Biochem Behav. 1994;47(1):183-186. DOI:10.1016/0091-3057(94)90129-5