ChemicalBook CAS DataBase List 263399-35-5

263399-35-5

Name	(±)12,13-DiHOME
CAS	263399-35-5
Molecular Formula	C18H34O4
MDL Number	MFCD12912337
Molecular Weight	314.46
MOL File	263399-35-5.mol

Chemical Properties

Boiling point	476.0±30.0 °C(Predicted)
density	1.015±0.06 g/cm3(Predicted)
storage temp.	Store at -20°C
solubility	DMF: 20 mg/ml,DMSO: 20 mg/ml,Ethanol: 20 mg/ml,PBS (pH 7.2): 10 μ g/ml
form	Liquid
pka	4.78±0.10(Predicted)
color	Colorless to light yellow

Safety Data

Symbol(GHS)	GHS02,GHS07
Signal word	Danger
Hazard statements	H225-H319-H336
Precautionary statements	P210-P240-P241-P242-P243-P261-P264-P271-P280-P303+P361+P353-P304+P340-P305+P351+P338-P312-P337+P313-P370+P378-P403+P233-P403+P235-P405-P501

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Animal Model:	Mice fed a high-fat diet^[1]
Dosage:	1 μg/kg
Administration:	Retro-orbitally injection; once daily for 2 weeks
Result:	Displayed no effects on body weight, glucose tolerance or circulating nonesterified FA. Increased BAT-specific lipid uptake and improved oral lipid tolerance. Increased radiolabeled FA uptake (Fig. 3f) and glucose uptake.

Animal Model:	To explore the biosynthesis of (±)12, 13-dihome in mice in vivo^[1]
Dosage:
Administration:	7-d cold challenge in mice: mice treated with norepinephrine (NE) for 30 min and exposed to 4°C-cold for 1 h
Result:	Result: Increased in the circulation of male mice exposed to cold, but not female mice. And also, the enzymes producing 12,13-diHOME were uniquely induced in BAT by cold stimulation.

263399-35-5

Chemical Properties

Safety Data

Hazard Information

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Definition

in vivo

storage

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