ChemicalBook CAS DataBase List 25249-16-5

25249-16-5

Name	POLY(2-HYDROXYETHYL METHACRYLATE)
CAS	25249-16-5
Molecular Formula	C6H10O3
MDL Number	MFCD00084374
Molecular Weight	130.14
MOL File	25249-16-5.mol

Chemical Properties

density	1.15 g/mL at 25 °C(lit.)
Tg	55
refractive index	1.5119
storage temp.	4°C, away from moisture
solubility	ethanol: 120 mg/mL
form	powder
color	White to off-white
biological source	synthetic (organic)
Cosmetics Ingredients Functions	BINDING
InChI	1S/C6H10O3/c1-5(2)6(8)9-4-3-7/h7H,1,3-4H2,2H3
InChIKey	WOBHKFSMXKNTIM-UHFFFAOYSA-N
SMILES	CC(=C)C(=O)OCCO
EPA Substance Registry System	2-Propenoic acid, 2-methyl-, 2-hydroxyethyl ester, homopolymer (25249-16-5)

Safety Data

Safety Statements	24/25 less more
WGK Germany	3
TSCA	TSCA listed
Storage Class	11 - Combustible Solids

Hazard Information

Uses

pHEMA scaffolds are used in tissue engineering. It can be used in hydrogels for biomedical applications, as sorbents for metal ions.pHEMA has been used in applications such as soft contact lenses, in drug delivery systems, and in kidney dialysis membranes.Nanoparticles of pHEMA may be employed as a carrier for controlled delivery of anticancer and antitumor drugs.

Uses

Poly(2-hydroxyethyl methacrylate) has been used:

as a nonadhesive substrate in the preparation of single cell suspensions
to implant into mice cornea for corneal micropocket assay
to coat the well plates for sphere assay using adipose-derived mesenchymal stem cells

Definition

ChEBI: An acrylate macromolecule, composed of repeating 2-hydroxyethyl 2-methylpropanoate units.

General Description

Solid Poly(2-hydroxyethyl methacrylate) (pHEMA) is brittle, while pHEMA hydrogel is a soft material. Glass transition temperature for pHEMA hydrogels is reduced by increasing a content of water in the matrix. Macromolecular properties in pHEMA are characterized by non-covalent interactions of hydrogen-bonds among the polymer chains as well as the hydrated water molecules. The presence of polar groups of hydroxyl and carboxyl on each repeat unit makes this polymer compatible with water. The hydrophobic a-methyl groups of the backbone convey hydrolytic stability to the polymer and enhance mechanical strength of the polymer matrix.

Biochem/physiol Actions

Poly(2-hydroxyethyl methacrylate) is an acrylic compound and has dental usage. It is mainly used to inhibit cell adhesion to growth surfaces in culture vessels.

Solubility in organics

DMF, methanol, methyl cellosolve

Spectrum Detail

Supplier

Shanghai Wanna Juhe Polymer Technology Co., Ltd

Telephone 13661897211

Websitehttp://www.wannapolymer.com/

Jinan Ruiyao Mingzhi Medical Technology Co., Ltd

Telephone15662630077 15662630077

Website

Dalian Meilun Biotech Co., Ltd.

Telephone0411-62910999 13889544652

Websitehttp://www.meilunbio.com/

Shanghai Qianhao Biotechnology Co., LTD

Telephone 13524877553

Websitehttps://www.qhaochem.com/

Meryer (Shanghai) Chemical Technology Co., Ltd.

Telephone4006356688 18621169109

Websitehttp://www.x-labseek.com/

Sinopharm Chemical Reagent Co,Ltd.

Telephone86-21-63210123

Websitehttp://www.reagent.com.cn

Spectrum Chemical Manufacturing Corp.

Telephone021-021-021-67601398-809-809-809 15221380277

Websitehttps://www.spectrumchemical.com/OA_HTML/index.jsp?minisite=10020&respid=22372&language=US

HangZhou YuHao Chemical Technology Co., Ltd.

Telephone0571-82693216

Websitehttp://www.yuhaochemical.com

Shanghai Macklin Biochemical Co.,Ltd.

Telephone15221275939 15221275939

Websitehttp://www.macklin.cn

Sigma-Aldrich

Telephone021-61415566 800-8193336

Websitehttps://www.sigmaaldrich.cn

Shanghai YuanYe Biotechnology Co., Ltd.

Telephone 13636370518

Websitehttps://www.shyuanye.com

Shenzhen Regent Biochemical Technology Co., Ltd.

Telephone0755-85201366 18938635012

Websitehttp://www.regentsciences.com/

Rhawn Reagent

Telephone400-400-1332688 18019345275

Websitehttp://www.rhawn.cn

Tianjin heowns Biochemical Technology Co., Ltd.

Telephone400-6387771-6039 18920764717

Websitehttp://www.heowns.com

Guangdong wengjiang Chemical Reagent Co., Ltd.

Telephone0751-2815688 13927872512

Websitehttp://www.wj-chem.com

Zhengzhou Alfa Chemical Co.,Ltd

Telephone +86-18530059196

Websitehttps://www.chemicalbook.com/manufacturer/zhengzhou-alfa-chemical-276/

Dideu Industries Group Limited

Telephone +8617392712697

Websitehttps://www.dideu.com

Henan Weituxi Chemical Technology Co., Ltd.

Telephone0371-63284658 18135795563

Websitehttps://www.chemicalbook.com/supplier/15004346/

1of4

Related Products

Send Inquriy