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Aramchol is a fatty acid conjugate that exhibits?hypocholesterolemic effects. Studies have shown that aramchol?suppresses the activity of?stearoyl-CoA desaturase (SCD), which leads to reduction of obesity, fatty liver and insulin resistance.

Arachidyl amido cholanoic acid (Aramchol) is a cholesterol solubilizer th at has the potential to prevent and dissolves cholesterol gallstones in inbred mice and in human gallbladder bile ex vivo.''Aramchol is a bile salt fatty acid conjugate (BAFAC) of arachidic acid and cholic acid. It has been shown to reduce liver f at by a dual mechanism of action. It inhibits the activity of liver stearoyl coenzyme A desaturase 1 (SCD1)decreasing the synthesis of fatty acids. In additionit activates cholesterol efflux by stimulating the adenosine triphosphate–binding cassette transporter A1 (ABCA1). Aramchol has been investigated for treatment for nonalcoholic steatohepatitisor NASH.