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1-Palmitoyl-2-12-PAHSA-3-oleoyl-sn-glycerol is a triacylglycerol that contains palmitic acid at the sn-1 position, the fatty acid ester of hydroxy fatty acids (FAHFA) 12-PAHSA at the sn-2 position, and oleic acid at the sn-3 position. It is an endogenous triacylglycerol that has been found in the lipid extract of mouse adipose tissue.¹ FAHFA-containing triacylglycerol levels are greater than 100-fold higher than non-esterified FAHFAs in mouse adipose tissues, indicating that triacylglycerols act as intracellular storage reservoirs for FAHFAs.

1. Tan, D., Ertunc, M.E., Konduri, S., et al. Discovery of FAHFA-containing triacyglycerols and their metabolic regulation J. Am. Chem. Soc. 141(22),8798-8806(2019).