ChemicalBook CAS DataBase List 2440-22-4

2440-22-4

Name	2-(2H-Benzotriazol-2-yl)-p-cresol
CAS	2440-22-4
EINECS(EC#)	219-470-5
Molecular Formula	C13H11N3O
MDL Number	MFCD00022903
Molecular Weight	225.25
MOL File	2440-22-4.mol

Chemical Properties

Melting point	125.5-129.5 °C(lit.)
Boiling point	bp10 225°
density	1.38
vapor pressure	0Pa at 20℃
refractive index	1.5600 (estimate)
Fp	54°C
storage temp.	15-25°C
solubility	DMSO (Slightly), Methanol (Slightly)
form	Solid
pka	8.15±0.43(Predicted)
color	Off-White to Pale Yellow
Water Solubility	173μg/L at 20℃
Merck	3447
Stability:	Hygroscopic
InChIKey	MCPKSFINULVDNX-UHFFFAOYSA-N
LogP	4.2 at 25℃
CAS DataBase Reference	2440-22-4(CAS DataBase Reference)
NIST Chemistry Reference	Phenol, 2-(2H-benzotriazol-2-yl)-4-methyl-(2440-22-4)
EPA Substance Registry System	2440-22-4(EPA Substance)

Safety Data

Hazard Codes	Xi
Risk Statements	R36/37/38:Irritating to eyes, respiratory system and skin . less more
Safety Statements	S22:Do not breathe dust . S24/25:Avoid contact with skin and eyes . less more
WGK Germany	1
RTECS	GO6860000
HS Code	29339900
Toxicity	LD50 oral in mouse: 6500mg/kg less more

Hazard Information

Chemical Properties

Light yellow powder

Uses

2(2-Hydroxy-5-methylphenyl)benzotriazol is an UV adsorber for use in plastics, cosmetics, dental materials, acrylic materials, dyes, etc.

Uses

An ultraviolet light absorber for stabilizing plastics and other organic materials against discoloration and deterioration.

Uses

Drometrizole is an intermediate reactant in the synthesis of UV light absorbers for polyester fibers.

Application

Intermediate reactant in the synthesis of UV light absorbers for polyester fibers
Reactant for synthesis of:
Benzotriazole UV absorbers with a blocked hydroxy group for us in UV curable paint
Maleimide-bound benzotriazole monomer to use for emulsion polymerization
Used in:
Microstereophotolithography and shape memory alloy for fabrication of miniaturized actuators
PVS and wood / PVC composites as a stabilizer
Acrylonitrile-butadiene-styrene as a UV absorber.

Definition

Drometrizole is a member of triazoles.

Flammability and Explosibility

Notclassified

Toxicity evaluation

The mutagenicity study of drometrizole was performed using Salmonella typhimurium strains TA1538 and TA98 with metabolic activation in the Ames’ test. Spot test (10 and 100 mg drometrizole/plate) and top agar method (50 and 100 mg drometrizole/plate) were conducted. The results showed that drometrizole was not mutagenic.Mice and rats were administered 5.0 or 10.0 g/kg of drometrizole in sunflower oil by stomach tube intubation. After body weight and behaviour were monitored for 3 weeks, acute toxicity of drometrizole was evaluated to be low. The oral lethal dose (LD50) of drometrizole in mice was reported to be 6.5 g/kg and > 5.0g/kg. Oral toxicity was evaluated in rats for nail care cosmetics containing 1%, 0.3% and 0.03% of drometrizole. The LD50 of products containing 1% of drometrizole was > 15.0 g/kg. The LD50 of products containing 0.3% and 0.03% drometrizole was > 5.0 g/kg. No acute toxicity was observed in these treatments.

Material Safety Data Sheet(MSDS)

Questions And Answer

Characterization
Drometrizole is an ultraviolet light absorber (UVA) of the hydroxyphenyl benzotriazole class, imparting good light stability to a wide variety of polymers. ;
Applications
Drometrizole provides ultraviolet protection in a wide variety of polymers including styrene homoand copolymers, engineering plastics such as polyesters and acrylic resins, polyvinyl chloride, and other halogen containing polymers and copolymers (e.g. vinylidenes), acetals and cellulose esters. Elastomers, adhesives, polycarbonate blends, polyurethanes, and some cellulose esters and epoxy materials also benefit from the use of Drometrizole.
;
Features/benefits
Drometrizole features a strong absorption of ultraviolet radiation in the 300-400 nm region. It also has a high degree of photostability over long periods of light exposure. The high absorbance combined with photostability and the ability to release absorbed energy in non sensitizing ways make Drometrizole an effective stabilizer against the effects of ultraviolet light. ;
Guidelines for use
The use levels of Drometrizole range between 0.10% and 0.50%, depending on substrate and performance requirements of the final application. Drometrizole can be used alone or in a variety of blends and combinations with Ciba IRGAFOS®, Ciba IRGANOX® and Ciba CHIMASSORB® stabilizers where often a synergistic performance is observed. Drometrizole may react with various heavy metal ions to form salts or complexes. For example, if Drometrizole comes into contact with iron or cobalt ions, colored complexes are formed. Reducing and oxidizing agents used in polymerization and curing processes have no effect on the stability of Drometrizole. ;
Physical Properties
;
Safety
In accordance with good industrial practice, handle with care and avoid unnecessary personal contact. Protect skin. Prevent contamination of the environment. Avoid dust formation and ignition sources. ;

Spectrum Detail

Well-known Reagent Company Product Information

Supplier

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Syntechem Co.,Ltd

Telephone

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Tianjin heowns Biochemical Technology Co., Ltd.

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2440-22-4

Chemical Properties

Safety Data

Hazard Information

Chemical Properties

Uses

Uses

Uses

Application

Definition

Flammability and Explosibility

Toxicity evaluation

Material Safety Data Sheet(MSDS)

Questions And Answer

Characterization

Applications

Features/benefits

Guidelines for use

Physical Properties

Safety

Spectrum Detail

Well-known Reagent Company Product Information

Supplier

Related Products