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RET-IN-3 is a is a selective RETV804M kinase inhibitor.

RET-IN-3 (compound 34) is a selective RETV804M kinase inhibitor, with an IC50 of 19 nM[1].

[1] Rebecca Newton, et al. Discovery and Optimization of wt-RET/KDR-Selective Inhibitors of RET V804M Kinase. ACS Med Chem Lett. 2020 Feb 28;11(4):497-505. DOI:10.1021/acsmedchemlett.9b00615