23109-94-6

tetranor-PGFM is the major urinary metabolite of PGF_2α. Normal healthy females excrete 7-13 μg of tetranor-PGFM per day compared to 11-59 μg/24 hours for healthy males. In pregnant females, tetranor-PGFM levels in the urine are 2 to 5-fold higher and diminish to pre-pregnancy levels soon after labor.

tetranor-PGFM is the major urinary metabolite of Dinoprost (HY-12956)[1].

ChEBI: 2,3,4,5-tetranor-prostaglandin FM is a prostanoid that is prostaglandin E2-UM in which the oxo group at position 9 has been reduced to the corresponding alcohol (alpha-configuration). It has a role as a metabolite. It is a prostanoid, an oxo dicarboxylic acid, a secondary alcohol and a ketone.

[1] Granstr?m E, et al. The structure of a urinary metabolite of prostaglandin F2a in man. J Am Chem Soc. 1969 Jun 4;91(12):3398-400. DOI:10.1021/ja01040a067