230-07-9

4,7-Phenanthroline was used in preparation of:

• cyclic tetranuclear half-sandwich ruthenium(II) complexes
• positively charged homochiral cyclic trinuclear metallacalix[3]arene species

ChEBI: 4,7-phenanthroline is a phenanthroline.

4,7-Phenanthroline reacts with ruthenium carbonyl to yield cyclometalated derivatives.

This hygroscopic reagent (FWfree-base = 180.21 g/mol; M.P. = 172-174°C; CAS 230-07-9), is a non-chelating isomer of 1,10-phenanthroline. Before inferring that the action of 1,10-phenanthroline is metal ion chelation, one should also assess the inhibitory effect of this non-chelating isomer. If a similar degree of inhibition is observed with both, one may assume that the effect has nothing to do with chelation an essential metal ion activator. See also 1,10-Phenanthroline; 1,-7Phenanthroline Target (s) : aldehyde dehydrogenase; leucyl aminopeptidase, weakly inhibited; nitrilase ; pyroglutamyl-peptidase II, or thyrotropin-releasing-hormone-degrading ectoenzyme.