ChemicalBook CAS DataBase List 228544-65-8

228544-65-8

Name	N-[2,6-BIS(1-METHYLETHYL)PHENYL]-N'-[4-[(4-NITROPHENYL)THIO]PHENYL]UREA
CAS	228544-65-8
Molecular Formula	C25H27N3O3S
MDL Number	MFCD10687104
Molecular Weight	449.57
MOL File	228544-65-8.mol

Chemical Properties

Boiling point	535.0±50.0 °C(Predicted)
density	1.24±0.1 g/cm3(Predicted)
storage temp.	Store at +4°C
solubility	Soluble to 100 mM in DMSO
form	Powder
pka	13.79±0.70(Predicted)
color	Light yellow to yellow

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Animal Model:	Male Wistar rats (250-300 g body weight), fed a standard diet and tap water ad libitum^[2]
Dosage:	50 mg/kg/day
Administration:	Administered as an admixture to the fat-cholesterol diet for 5 days
Result:	Improved the overall myocardial ischaemia-reperfusion injury outcomes in the diabetic-hypercholesterolaemic rats by suppressing arrhythmogenesis as well as by reducing myocardial necrosis, aside from remarkable hypolipidaemic activity.

228544-65-8

Chemical Properties

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Biological Activity

in vivo

IC 50

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