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N,N-diethanol amine-PEG4-tert-butyl ester is a PEG reagent with two hydroxyl moieties. The t-butyl group can be deprotected under acidic conditions. The hydrophilic PEG spacers increase the compounds water solubility in aqueous media.

N,N-Diethanol amine-PEG4-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

PEGs; Alkyl/ether

[1] An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 DOI:10.1016/j.ebiom.2018.09.005