2260-08-4

Name	Acetiromate
CAS	2260-08-4
Molecular Formula	C15H9I3O5
MDL Number	MFCD00865720
Molecular Weight	649.931
MOL File	2260-08-4.mol

Synonyms

Adecol Acetiromate Acetyltriiodothyroformic acid 3,5-Diiodo-4-(4-acetoxy-3-iodophenoxy)benzoic acid 4-(4-Acetoxy-3-iodophenoxy)-3,5-diiodobenzoic acid 4-(4-acetyloxy-3-iodophenoxy)-3,5-diiodobenzoic acid 4-(4-acetyloxy-3-iodo-phenoxy)-3,5-diiodo-benzoic acid

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Chemical Properties

Melting point	238°C
density	2.3074 (estimate)

Hazard Information

Originator

Acetiromate ,ZYF Pharm Chemical

Uses

Acetiromate is a thyroxine analogue. Acetiromate is an antilipidemic drug for hyperlipidemia[1].

Manufacturing Process

To 3 parts of 3,5-diiodo-4-(3-iodo-4-hydroxyphenoxy)benzoic acid 10 parts of acetic acid anhydride was added and mixture was heated on oil bath for some hours. In the result of this reaction amorphous precipitate was obtained. After recrystallization from glacial acetic acid 2.4 parts of 3,5-diiodo-4-(3-iodo-4- acetoxyphenoxy)benzoic acid were obtained.

Therapeutic Function

Antihyperlipidemic

References

[1] S Kumaoka. Long-term administration of 3,5-diodo-4(3'-iodo4'-acetoxyphenoxy) benzoic acid (acetiromate) in hyperlipidemic patients. Endocrinol Jpn. 1974 Aug;21(4):355-60. DOI:10.1507/endocrj1954.21.355

Supplier

TargetMol Chemicals Inc.

Telephone 15002134094

Websitehttps://www.targetmol.cn/

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