224186-05-4

Integracin B is a unusual ester and potent inhibitor of HIV-1.

Integracin B is an unusual ester of two structurally related alkylresorcinols first isolated from a fungus, Cytonaema sp., in 2002 as a potent inhibitor of HIV-1 integrase. With the exception of this initial report, integracin B has received little further attention.

Integracin B is an unusual ester of two structurally related alkylresourcinols first isolated from a fungus, Cytonaema sp., in 2002 as a potent inhibitor of HIV-1 integrase. With the exception of this initial report, Integracin B has received little further attention.

ChEBI: Integracin B is a benzoate ester obtained by the formal condensation of the hydroxy group of 5-(8-hydroxyundecyl)benzene-1,3-diol with 4,6-dihydroxy benzoic acid which is also substituted by a 8-hydroxyundecyl group at position 2. It is isolated from Cytonaema sp. and has anti-HIV-1 activity. It has a role as a metabolite and a HIV-1 integrase inhibitor. It is a member of resorcinols, a benzoate ester and a secondary alcohol.

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