221660-80-6

SCH 57790 is a selective muscarinic M(2) receptor antagonist, which releases acetylcholine and produces cognitive enhancement.

SCH 57790 is a selective antegonist for muscarinic M2 receptor, which increases acetylcholine release, and thus improves cognitive performance. SCH 57790 reverses Scopolamine (HY-N0296)-induced memory deficits in mice, without significant toxicity (100 mg/kg).

[1] Carey GJ, et al., SCH 57790, a selective muscarinic M(2) receptor antagonist, releases acetylcholine and produces cognitive enhancement in laboratory animals. Eur J Pharmacol. 2001 Nov 16;431(2):189-200. DOI:10.1016/s0014-2999(01)01440-6