221205-90-9

Pyrimisulfan is used as a herbicide for agricultural purposes. A novel rice herbicide.

ChEBI: N-{2-[(4,6-dimethoxypyrimidin-2-yl)(hydroxy)methyl]-6-(methoxymethyl)phenyl}-1,1-difluoromethanesulfonamide is a member of the class of pyrimidines that is pyrimidine which is substituted by a [2-{[(difluoromethyl)sulfonyl]amino}-3-(methoxymethyl)phenyl](hydroxy)methyl group at position 2 and by methoxy groups at positions 4 and 6. It is a member of pyrimidines, an aromatic ether, a sulfonamide, an organofluorine pesticide and a secondary alcohol.

Pyrimisulfan is commercially synthesised through a multi-step process that constructs its complex sulfonamide structure. The synthesis typically begins with the formation of a substituted pyrimidine ring, specifically 4,6-dimethoxypyrimidin-2-yl, which is then functionalized with a hydroxymethyl group. This intermediate is coupled with a methoxymethyl-substituted phenyl ring and finally reacted with difluoromethanesulfonyl chloride to form the sulfonamide linkage. The process involves precise control of reaction conditions to maintain stereochemistry and purity.

ALS inhibition

Herbicide