2205-73-4

Name	tiomesterone
CAS	2205-73-4
EINECS(EC#)	218-614-4
Molecular Formula	C24H34O4S2
Molecular Weight	450.65
MOL File	2205-73-4.mol

Synonyms

STA-307 tiomesterone Thiomesterone YUOZKOLALXNELS-SQVYRKCQSA-N 1α,7α-Bis(acetylthio)-17β-hydroxy-17α-methylandrost-4-en-3-one 1α,7α-Bis(acetylthio)-17β-hydroxy-17α-methylandrost-4-ene-3-one Androst-4-en-3-one, 1,7-bis(acetylthio)-17-hydroxy-17-methyl-, (1α,7α,17β)- S-[(1S,7R,8S,9S,10R,13S,14S,17S)-1-acetylsulfanyl-17-hydroxy-10,13,17-trimethyl-3-oxo-2,6,7,8,9,11,12,14,15,16-decahydro-1H-cyclopenta[a]phenanthren-7-yl] ethanethioate S-[(1S,7R,8S,9S,10R,13S,14S,17S)-1-ethanoylsulfanyl-17-hydroxy-10,13,17-trimethyl-3-oxo-2,6,7,8,9,11,12,14,15,16-decahydro-1H-cyclopenta[a]phenanthren-7-yl] ethanethioate ethanethioic acid S-[(1S,7R,8S,9S,10R,13S,14S,17S)-1-(acetylthio)-17-hydroxy-3-keto-10,13,17-trimethyl-2,6,7,8,9,11,12,14,15,16-decahydro-1H-cyclopenta[a]phenanthren-7-yl] ester

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Chemical Properties

Melting point	205-206°
alpha	D -66° (dioxane)
Boiling point	528.69°C (rough estimate)
density	1.1283 (rough estimate)
refractive index	1.4360 (estimate)

Hazard Information

Originator

Tiomesterone,Yick-Vik Chemicals and Pharmaceticals (H.K.) Ltd.

Uses

Tiomesterone is an anabolic steroid and a derivative of testosterone (T155000), the principal hormone of the testes, produced by the interstitial cells.

Definition

ChEBI: Tiomesterone is a 3-hydroxy steroid. It has a role as an androgen.

Manufacturing Process

4 g 17α-methyl-1,4,6-androstatriene-17β-ol-3-one are boiled in 12 ml thioacetic acid under reflux for 1.5 hours. This reaction mixture is thereafter concentrated in vacuum to dryness and the 1α,7α -diacetylthio-17β-hydroxy- 17-methylandrost-4-en-3-one is crystallized from the residue after treatment with methanol; melting point 202-204°C; [α]D = -74.6° (dioxane); λmax 237.5 nm.

Therapeutic Function

Anabolic

Supplier

Shanghai T&W Pharmaceutical Co., Ltd.

Telephone+86 21 61551611

Websitehttp://www.trustwe.com

Energy Chemical

Telephone021-58432009 400-005-6266

Websitehttp://www.energy-chemical.com

Shaanxi DIDU pharmaceutical and Chemical Co., Ltd

Telephone 15229059051

Websitehttp://www.dideu.cn

Wuhan senwayer century chemical Co.,Ltd

Telephone+undefined-27-86652399 +undefined13627115097

Websitehttp://www.senwayer.com/

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