217963-18-3

SCH00013 is a cardiotonic that primarily increases the sensitivity of muscle fibers to Ca++.

[1] Sugawara H et al. A novel cardiotonic agent SCH00013 acts as a Ca++ sensitizer with no chronotropic activity in mammalian cardiac muscle. J Pharmacol Exp Ther. 1998 Oct;287(1):214-22. PMID:9765340
[2] Tadano N et al. SCH00013, a novel Ca(2+) sensitizer with positive inotropic and no chronotropic action in heart failure. J Pharmacol Sci. 2005 Jan;97(1):53-60. DOI:10.1254/jphs.fp0040654
[3] Endoh M et al. Pharmacology of SCH00013: a novel Ca2+ sensitizer. Cardiovasc Drug Rev. 2001 Winter;19(4):345-66. DOI:10.1111/j.1527-3466.2001.tb00075.x