ChemicalBook CAS DataBase List 2173557-02-1

2173557-02-1

Name	Carbamic acid, N-[5-[2-[(cyclopropylcarbonyl)amino]-6-benzothiazolyl]-2-methyl-3-pyridinyl]-, tetrahydro-2H-pyran-4-yl ester
CAS	2173557-02-1
Molecular Formula	C23H24N4O4S
Molecular Weight	452.53
MOL File	2173557-02-1.mol

Chemical Properties

density	1.40±0.1 g/cm3(Predicted)
pka	10.02±0.70(Predicted)

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Animal Model:	C57BL/6 female mice (TNF-induced systemic inflammatory response syndrome)^[1]
Dosage:	3 mg/kg
Administration:	i.p. for 30 min, followed by injection with TNFα (0.25 μg/g)
Result:	Significantly reduced TNFα-induced temperature loss and ameliorated lethal shock in mice.