2166-14-5

Dimethyl 1,2,4,5-tetrazine-3,6-dicarboxylate is a reactive heteroaromatic azadiene with inverse electron demand that undergoes Diels-Alder reactions with a variety of dienophiles and isodieniphiles; it is used to prepare substituted 1,2-diazines, 1,2,4-triazines, pyrroles, pyridines, indolines, and related fused heterocycles.

3,6-Dimethyl 1,2,4,5-Tetrazine-3,6-dicarboxylate (CAS# 2166-14-5) can be used in the synthesis of N-?substituted dibenzoazepine-?pyridazine derivatives via Diels-Alder reaction of dibenzoazepines with tetrazines for their use as potential neurologically active drugs.

Dimethyl 1,2,4,5-tetrazine-3,6-dicarboxylate is a very reactive diene which  is unstable to acid, base, H2O, or protic solvents and should be stored moisture-free and refrigerated.