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TAMRA (tetramethylrhodamine) is a well known fluorophore that has a long history of use in biomolecule labeling. TAMRA can serve as a FRET acceptor for FAM (fluorescein)._x000D_ TAMRA amine is a derivative having a primary amine group that can be conjugated with various electrophiles like activated esters, epoxides, etc., used in reductive amination reactions, and in enzymatic transamination.