Chemical Properties
White or off-white or pale beige crystals or crystalline powder, odorless, slightly bitter. Soluble in hot water, poorly soluble in water and ethanol. Melting point: 233-234°C (decomposition), melting point: 237-239°C. (+)-Dexrazoxane: [24584-09-6]. Crystallized from aqueous methanol-ether, melting point: 193°C. [α]D +11.35° (C = 5, dimethylformamide). Solubility (mg/ml): 10-12 (water), 35-43 (0.1 mol/L hydrochloric acid), 25-34 (0.1 mol/L sodium hydroxide), 6.7-10 (10% ethanol), 1 (methanol), 7.1-10 [water-dimethylformamide (1:1)], 9.7-14.5 [0.1 mol/L citrate buffer (Ph value 4)], 8.7-13 [0.1 mol/L boric acid buffer (Ph value 9)].
