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(S,R,S)-AHPC-C4-NH2 is a E3 ligase ligand-linker conjugate that is comprised of the (S,R,S)-AHPC based VHL ligand and a four carbon alkane linker used for EED-Targeted PROTAC.

(S,R,S)-AHPC-C4-NH2 is a synthesized E3 ligase ligand-linker conjugate that incorporates the (S,R,S)-AHPC based VHL ligand and a linker used for EED-Targeted PROTAC[1].

VHL

[1] Hsu JH, et al. EED-Targeted PROTACs Degrade EED, EZH2, and SUZ12 in the PRC2 Complex. Cell Chem Biol. 2019 Nov 26. pii: S2451-9456(19)30362-9. DOI:10.1016/j.chembiol.2019.11.004