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Δ²-trans Eicosenoic acid is an α,β-unsaturated fatty acid that is a bi-product of the synthesis of Δ²-cis eicosenoic acid. Δ²-cis eicosenoic acid and its salts have potential medical use for treating diabetes and improving lipid metabolism. A related compound, 2-octadecenoic acid, has been shown to improve liver function and decrease blood sugar in streptozocin-induced diabetic rats.¹

(2E)-Eicosenoic acid is an inhibitor of Mycobacterium tuberculosis protein tyrosine phosphatase A (PtpA). (2E)-Eicosenoic acid exhibits strong inhibitory activity against PtpA with an IC50 value in the low micromolar range. (2E)-Eicosenoic acid can be used for research on Mycobacterium tuberculosis infection[1].

ChEBI: Trans-2-icosenoic acid is an icosenoic acid in which the double bond is at the 2-3 position and has E configuration. It is an icosenoic acid and an alpha,beta-unsaturated monocarboxylic acid.

1. Iwamura, J., Hayashi, C., and Nozomu, T. Medicinal use of α,β-unsaturated fatty acids App. 377,407,1-5(1984).