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17-trans PGE₃ is an isomer of PGE₃ which could theoretically result from the COX metabolism of dietary trans-fatty acids. There are no published reports on the biological activity of this compound.

17-trans Prostaglandin E3 is a prostaglandin analog, and stimulates Nurr1-dependent transcriptional activity. 17-trans Prostaglandin E3 can be used for research of condition associated with Nurr1,such as cancer and autoimmune disease[1].

[1] Cheolhwan Yoon, et al. Prostaglandin analogs and uses thereof. Patent. US20210139435.