2108907-29-3

Branched fatty acid esters of hydroxy fatty acids (FAHFAs) are newly identified endogenous lipids regulated by fasting and high-fat feeding and associated with insulin sensitivity.1 13-SAHSA is a FAHFA consisting of stearic acid esterified to 13-hydroxy stearic acid. The levels of SAHSA are moderately elevated in the serum of glucose tolerant AG4OX mice, which overexpress the Glut4 glucose transporter specifically in adipose tissue.1 As other FAHFAs improve glucose tolerance, stimulate insulin secretion, and have anti-inflammatory effects, 13-SAHSA may be a bioactive lipid with roles in metabolic syndrome and inflammation.1WARNING This product is not for human or veterinary use.

[1] MARK M YORE. Discovery of a class of endogenous mammalian lipids with anti-diabetic and anti-inflammatory effects.[J]. Cell, 2014, 159 2: 318-332. DOI: 10.1016/j.cell.2014.09.035
[2] PRATIK ARYAL. Distinct biological activities of isomers from several families of branched fatty acid esters of hydroxy fatty acids (FAHFAs).[J]. Journal of Lipid Research, 2021: 100108. DOI: 10.1016/j.jlr.2021.100108