2095668-10-1

VIT-2763 (30, 100 mg/kg, orally twice daily for 36 days) decreases serum iron and prevented liver iron loading in Hbb^th3/+ mice^[1].
VIT-2763 did not change the total liver iron^[1].
VIT-2763 (30, 100 mg/kg, orally twice daily for 36 days) significantly corrects anemia and improved RBC parameters in Hbb^th3/+ mice. VIT-2763 decreases the percentage of ROS-positive RBCs in Hbb^th3/+ mice from 67% to 30%^[1].
VIT-2763 decreases apoptosis and extends the life span of RBCs in Hbb^th3/+ mice^[1].