20398-34-9

Adenosine 5′-diphosphate sodium salt is an adenine nucleotide phosphorylated into ATP by ATPase. This phosphorylation is a crucial part of cellular homeostatis as it allows energy storage and is involved in nucleic acid metabolism. ADP affects platelet activation through its interaction with ADP receptors P2Y1, P2Y12 and P2X1. Upon its conversion to adenosine by ecto-ADPases, platelet activation is inhibited via adenosine receptors.

Adenosine 5′-diphosphate (ADP) is an adenine nucleotide involved in energy storage and nucleic acid metabolism via its conversion into ATP by ATP synthases. ADP affects platelet activation through its interaction with ADP receptors P2Y1, P2Y12 and P2X1. Upon its conversion to adenosine by ecto-ADPases, platelet activation is inhibited via adenosine receptors.

Adenosine 5′-diphosphate sodium salt affects platelet activation through its interaction with ADP receptors P2Y1, P2Y12 and P2X1. Upon its conversion to adenosine by ecto-ADPases, platelet activation is inhibited via adenosine receptors.

Human Endogenous Metabolite

[1] Arts IC, et al. Adenosine 5'-triphosphate (ATP) supplements are not orally bioavailable: a randomized, placebo-controlled cross-over trial in healthy humans. J Int Soc Sports Nutr. 2012 Apr 17;9(1):16. DOI:10.1186/1550-2783-9-16
[2] Noel J. Cusack, et al. Effects of phosphate-modified analogs of adenosine 5′-diphosphate and adenosine 5′‐triphosphate at P2T-purinoceptors mediating human platelet activation by ADP. April 1996.
[3] Adenosine-5'-diphosphate