202590-69-0

Name	CIS-4-AMINO-5-CHLORO-2-METHOXY-N-(3-METHOXY-PIPERIDIN-4-YL)-BENZAMIDE
CAS	202590-69-0
Molecular Formula	C14H20ClN3O3
MDL Number	MFCD07784009
Molecular Weight	313.78
MOL File	202590-69-0.mol

Synonyms

Ticalopride 202590-69-0 NORCISAPRIDE Unii-qng273A81o Ticalopride [inn] CIS-4-AMINO-5-CHLORO-2-METHOXY-N-(3-METHOXY-PIPERIDIN-4-YL)-BENZAMIDE 4-amino-5-chloro-2-methoxy-N-((3S,4R)-3-methoxypiperidin-4-yl)benzamide Benzamide, 4-amino-5-chloro-2-methoxy-N-[(3S,4R)-3-methoxy-4-piperidinyl]-

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Hazard Information

Uses

(+)-Norcisapride (Ticalopride) is a potent 5-HT4 agonist and a 5-HT3 antagonist. (+)-Norcisapride has activity in animals models of constipation[1].

IC 50

5-HT₄ Receptor; 5-HT₃ Receptor

References

[1] Liming Shao, et al. mu-Opioid/5-HT4 dual pharmacologically active agents-efforts towards an effective opioid analgesic with less GI and respiratory side effects (Part I). Bioorg Med Chem Lett. 2009 Oct 1;19(19):5679-83. DOI:10.1016/j.bmcl.2009.08.016

Supplier

Shanghai Sinch Parmaceuticals Tech. Co. Ltd.

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Hefei Hirisun Pharmatech Co., Ltd

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TargetMol Chemicals Inc.

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