ChemicalBook CAS DataBase List 156223-05-1

156223-05-1

Name	3-(2,4-dimethoxybenzylidene)anabaseine
CAS	156223-05-1
Molecular Formula	C19H22Cl2N2O2
MDL Number	MFCD00941364
MOL File	156223-05-1.mol

Synonyms

DMXB DMXB-A GTS-21HCl GTS 21 2HCl DMBX-anabaseine GTS-21 (DMXB-A) GTS 21 2HCl(DMXBA) GTS21;GTS 21;GTS-21 GTS 21 2hydrochloride GTS-21 (hydrochloride) GTS 21 dihydrochloride 3-(2,4-dimethoxybenzylidene)anabaseine 3-(2,4)-DiMethoxybenzylidineanabaseine GTS 21 DIHYDROCHLORIDE;DMXB-A;DMBX-ANABASEINE 3-(2,4-Dimethoxybenzylidene)-anabaseine dihydrochloride 3-(2,4-Dimethoxy-benzyl)-3,4,5,6-tetrahydro-[2,3']bipyridinyl 3-(2,4-DiMethoxy-benzyl)-3,4,5,6-tetrahydro-[2,3']bipyridinyl Dihydrochloride 3-[(2,4-dimethoxyphenyl)methylene]-3,4,5,6-tetrahydro-2,3'-Bipyridine Dihydrochloride (3E)-3-[(2,4-Dimethoxyphenyl)methylene]-3,4,5,6-tetrahydro-2,3'-Bipyridine dihydrochloride 3-[(3E)-3-[(2,4-dimethoxyphenyl)methylidene]-5,6-dihydro-4H-pyridin-2-yl]pyridine dihydrochloride

Chemical Properties

Melting point	216-217℃ (decomposition)
storage temp.	2-8°C
solubility	H2O: >5mg/mL
form	powder
color	faint yellow to dark yellow
Water Solubility	H2O: >5mg/mL
InChIKey	RPYWXZCFYPVCNQ-RVDMUPIBSA-N

Safety Data

Symbol(GHS)	GHS07
Signal word	Warning
Hazard statements	H302-H315-H319-H335
Precautionary statements	P261-P305+P351+P338
WGK Germany	3
RTECS	DW1764860

Hazard Information

Spectrum Detail

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Animal Model:	C57BL6 mice were irradiated with 12 Gy to induce a mouse model of Radiation induced lung injury (RILI)^[3]
Dosage:	4 mg/kg
Administration:	I.p.; 1, 3, 7, 14 and 21 days
Result:	Reduces lung inflammatory infiltrate and fibrosis in radiation treated mice.

156223-05-1

Chemical Properties

Safety Data

Hazard Information

Uses

Biochem/physiol Actions

in vivo

IC 50

storage

Spectrum Detail

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