20007-87-8

Cyclopenin is an inhibitor of acetylcholinesterase (AChE; IC₅₀ = 2.04 μM for human recombinant AChE) that is produced by Penicillium. It exhibits greater than 2,000-fold selectivity over recombinant equine butyrylcholinesterase with an IC₅₀ value greater than 4,080 μM. Cyclopenin also has antibacterial activity against E. coli and M. pyogenes.

ChEBI:(-)-cyclopenine is an epoxide.

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