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Acetyl dipeptide-1 cetyl ester is a lab-engineered synthetic peptide that combines acetic acid and cetyl alcohol with dipeptide-1, a peptide composed of amino acids arginine and tyrosine. Dipeptide-1 is found naturally in the body and plays a role in maintaining skin’s elasticity. Acetyl dipeptide-1 cetyl ester is a cosmeceutical peptide. It increases the expression of the genes encoding the skin barrier function proteins AQP3, FLG, caspase-14, and cytokeratin 10 in primary human keratinocytes. Acetyl dipeptide-1 cetyl ester reduces glyoxal-induced formation of advanced glycation end products (AGEs) in primary human fibroblasts.

Acetyl dipeptide-1 cetyl ester (Calmosensine) is a bioactive peptide with anti-aging effect and has been reported used as a cosmetic ingredient.

Acetyl Dipeptide-1 Cetyl ester is a lipopeptide, i.e., a molecule consisting of a lipid connected to a peptide. It is a lab-engineered peptide blend made with amino acids arginine and tyrosine and can be found in skincare, cosmetics, and make-up formulations. In skincare, Acetyl Dipeptide-1 Cetyl ester is primarily used to stimulate elastin production and to help prevent skin sagging by resisting gravity. It is famed as a relaxant that helps prevent the visible signs of aging with fine lines and wrinkles.