ChemicalBook CAS DataBase List 195822-23-2

195822-23-2

Name	LQZ-7I
CAS	195822-23-2
Molecular Formula	C20H14F2N4
MDL Number	MFCD00607076
Molecular Weight	348.35
MOL File	195822-23-2.mol

Chemical Properties

Melting point	203 °C(Solv: ethanol (64-17-5))
Boiling point	470.3±45.0 °C(Predicted)
density	1.390±0.06 g/cm3(Predicted)
storage temp.	Keep in dark place,Inert atmosphere,Room temperature
solubility	DMSO: 125 mg/mL (358.83 mM)
form	A solid
pka	2.56±0.59(Predicted)
color	Light yellow to green yellow

Safety Data

Symbol(GHS)	GHS05,GHS07
Signal word	Danger
Hazard statements	H302+H312+H332-H314
Precautionary statements	P501-P261-P270-P271-P264-P280-P362+P364-P303+P361+P353-P301+P330+P331-P301+P312+P330-P304+P340+P310-P305+P351+P338+P310-P405

Hazard Information

Supplier

Shanghai Lollane Biological Technology Co.,Ltd.

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Shanghai EFE Biological Technology Co., Ltd.

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ShangHai Biochempartner Co.,Ltd

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Shanghai Chaolan Chemical Technology Center

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Beijing Jin Ming Biotechnology Co., Ltd.

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Shanghai Hongye Biotechnology Co. Ltd

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DC Chemicals

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cjbscvictory

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Jinan Jiuli Biotechnology Co. , Ltd.

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Beijing Jin Ming Biotechnology Co., Ltd.

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Bide Pharmatech Ltd.

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InvivoChem

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TargetMol Chemicals Inc.

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Shanghai Maclean Biochemical Technology Co., LTD

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Cell Line:	PC- 3 or C4-2 cells
Concentration:	10 μM
Incubation Time:	0-6 hours
Result:	Reduced the expression of survivin.

Animal Model:	6-week old male NSG mice
Dosage:	100 mg/kg; 200 μL vehicle (90% corn oil/10% DMSO)
Administration:	Oral gavage every other day for a total of ten treatments
Result:	Significantly suppressed tumor growth without any notable adverse effect on the mice as indicated by lacking changes in body weight and in wet weight of major organs at the end of the study.

195822-23-2

Chemical Properties

Safety Data

Hazard Information

Biological Activity

in vitro

in vivo

target

Supplier